this book has no rival either in the country or abroad.From the Foreword to the book by Prof J R IsaacProfessor Emeritus, IIT-Bombay & Retired Advisor, NIIT Ltd., New DelhiThis book is a time tested reference covering the architecture, hardware organisation, circuit design and maintenance of the IBM PC series and its clones. The design concepts and techniques discussed facilitate application of chip-level analysis in the troubleshooting of any common PC.This thoroughly revised second edition encapsulates the rapid changes in technology, architecture, engineering and built-in capabilities of the personal computer. Salient Features:Detailed coverage of hardware circuits, software concepts and interfaces, test equipments and diagnostic aids
Complete hardware design at the systems and components level of an IBM PC and its clones
Common problems with their detailed troubleshooting procedure
Practical tips for troubleshooting and quick diagnosis
Systematic analysis of the POST sequence.The book is highly recommended for universities, research laboratories, libraries, faculty, students, and educational, training and service centers as well as for the ever-growing electronic hobbyists and entrepreneurs. The author, Mr Govindarajalu is a successful technocrat with over 30 years of experience in the computer industry covering R&D, manufacturing, maintenance, teaching, technical support and training.CD includes: Video on PC Assembling: Step-by-step procedure of assembling a PC (supplement to Chapter 13), followed by a live demonstration; Anti-Virus software: Trial version of Vx2000 plus' - an antivirus package from K7 COMPUTING; About Microcode's certification course of PC Hardware Who was first!Contents include: 1. Microcomputer System explains hardware organisation of the digital computer; overviews advanced techchniques including multiprogramming, virtual memory and cache memory.2. Peripheral Devices gives concepts used in different peripheral devices of the PC.3. PC Hardware Overview presents architecture of the original IBM PC and its followers.4. Hardware Components and ICs presents an introduction to digital electronics and common ICs used in PC Circuits.5. Microprocessors in PC describes microprocessors used in different versions of the PCs starting from the original IBM PC to today's Pentium 4.6. Support Chips in the Motherboard deals with the dumb and intelligent support chips used with the microprocessors. 7. PC Bus and Motherboard explains the different bus types and the different functional sections in the motherboard nucleus. 8. Printer Controller describes the different modes of the parallel ports starting with the traditional centronics interface.9. Floppy Disk Controller describes the floppy disk controllers and the interface of floppy disk drive and hard disk drive.10. Hard Disk Controller Subsystem describes the disk controllers and the interfaces of floppy disk drive/hard disk drive11. Display Adapter deals with the principle of operation and the functional sections of the CRT display controller.12. Serial Interfaces describes the various scribal interfaces in the PC.13. Installation and Preventive Maintenance deals with the essential aspects of system integration, installation and preventive maintenance of the PC.14. Troubleshooting deals exclusively with the troubleshooting problems in PCs along with step-by-step troubleshooting guidelines, based on 8088-PC, the best platform to learn.15. Introduction to Networking presents an overview of networking concepts.16. RISC and Servers covers advanced personal computer topics: RISC and Servers.
Ibm Pc And Clones By Govindarajulu Pdf Download
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A method is disclosed for isolating and identifying modified para-nitrobenzyl esterases which exhibit improved stability and/or esterase hydrolysis activity toward selected substrates and under selected reaction conditions relative to the unmodified para-nitrobenzyl esterase. The method involves preparing a library of modified para-nitrobenzyl esterase nucleic acid segments (genes) which have nucleotide sequences that differ from the nucleic acid segment which encodes for unmodified para-nitrobenzyl esterase. The library of modified para-nitrobenzyl nucleic acid segments is expressed to provide a plurality of modified enzymes. The clones expressing modified enzymes are then screened to identify which enzymes have improved esterase activity by measuring the ability of the enzymes to hydrolyze the selected substrate under the selected reaction conditions. Specific modified para-nitrobenzyl esterases are disclosed which have improved stability and/or ester hydrolysis activity in aqueous or aqueous-organic media relative to the stability and/or ester hydrolysis activity of unmodified naturally occurring para-nitrobenzyl esterase. 43 figs.
A method for isolating and identifying modified para-nitrobenzyl esterases which exhibit improved stability and/or esterase hydrolysis activity toward selected substrates and under selected reaction conditions relative to the unmodified para-nitrobenzyl esterase. The method involves preparing a library of modified para-nitrobenzyl esterase nucleic acid segments (genes) which have nucleotide sequences that differ from the nucleic acid segment which encodes for unmodified para-nitrobenzyl esterase. The library of modified para-nitrobenzyl nucleic acid segments is expressed to provide a plurality of modified enzymes. The clones expressing modified enzymes are then screened to identify which enzymes have improved esterase activity by measuring the ability of the enzymes to hydrolyze the selected substrate under the selected reaction conditions. Specific modified para-nitrobenzyl esterases are disclosed which have improved stability and/or ester hydrolysis activity in aqueous or aqueous-organic media relative to the stability and/or ester hydrolysis activity of unmodified naturally occurring para-nitrobenzyl esterase.
A method is disclosed for isolating and identifying modified para-nitrobenzyl esterases. These enzymes exhibit improved stability and/or esterase hydrolysis activity toward selected substrates and under selected reaction conditions relative to the unmodified para-nitrobenzyl esterase. The method involves preparing a library of modified para-nitrobenzyl esterase nucleic acid segments (genes) which have nucleotide sequences that differ from the nucleic acid segment which encodes for unmodified para-nitrobenzyl esterase. The library of modified para-nitrobenzyl nucleic acid segments is expressed to provide a plurality of modified enzymes. The clones expressing modified enzymes are then screened to identify which enzymes have improved esterase activity by measuring the ability of the enzymes to hydrolyze the selected substrate under the selected reaction conditions. Specific modified para-nitrobenzyl esterases are disclosed which have improved stability and/or ester hydrolysis activity in aqueous or aqueous-organic media relative to the stability and/or ester hydrolysis activity of unmodified naturally occurring para-nitrobenzyl esterase. 43 figs.
Estos archivos de anuncios de servicio público se pueden descargar libremente para su uso en la formación, transmisiones de audio, etc.(These public service announcement files can be freely downloaded for use in training, audio broadcasts, etc.)
The number of publicly available parasitic worm genome sequences has increased dramatically in the past three years, and research interest in helminth functional genomics is now quickly gathering pace in response to the foundation that has been laid by these collective efforts. A systematic approach to the organisation, curation, analysis and presentation of these data is clearly vital for maximising the utility of these data to researchers. We have developed a portal called WormBase ParaSite ( ) for interrogating helminth genomes on a large scale. Data from over 100 nematode and platyhelminth species are integrated, adding value by way of systematic and consistent functional annotation (e.g. protein domains and Gene Ontology terms), gene expression analysis (e.g. alignment of life-stage specific transcriptome data sets), and comparative analysis (e.g. orthologues and paralogues). We provide several ways of exploring the data, including genome browsers, genome and gene summary pages, text search, sequence search, a query wizard, bulk downloads, and programmatic interfaces. In this review, we provide an overview of the back-end infrastructure and analysis behind WormBase ParaSite, and the displays and tools available to users for interrogating helminth genomic data. Copyright 2016 The Authors. Published by Elsevier B.V. All rights reserved. 2ff7e9595c
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